Collapsing glomerulopathy in systemic lupus erythematosus
نویسندگان
چکیده
منابع مشابه
Collapsing glomerulopathy in systemic lupus erythematosus: an extreme form of lupus podocytopathy?
Collapsing glomerulopathy (CG) describes a pattern of glomerular injury, the main feature of which is severe injury to podocytes with loss of markers of differentiation, proliferation of podocytes and/or parietal epithelial cells filling Bowman’s space, and global or segmental collapse of the capillary tuft (1–4). Multiple etiologies of CG have been described, including certain viral infections...
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BACKGROUND AND OBJECTIVES Collapsing glomerulopathy is a podocytopathy with segmental or global wrinkling and collapse of capillary walls and overlying epithelial cell proliferation. Idiopathic collapsing glomerulopathy is a distinct clinicopathologic entity with significant proteinuria, poor response to immunosuppressive therapy, and rapid progression to renal failure. Collapsing glomerulopath...
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Collapsing glomerulopathy is a devastating renal disease that primarily affects African Americans and associates with numerous etiologies, such as HIV and autoimmune disease. The presence of APOL1 risk alleles associates with HIV-associated collapsing glomerulopathy, but it is unknown whether these risk alleles also associate with systemic lupus erythematosus (SLE) -associated collapsing glomer...
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A 48-year-old African American female with a history of essential hypertension presented with fatigue of several weeks’ duration. Her only home medication was amlodipine. The patient denied illicit drug use. Apart from a purplish malar rash, physical examination was noncontributory. The patient did give a history of a photosensitive skin eruption on both arms in the past. Laboratory data includ...
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ژورنال
عنوان ژورنال: BMJ Case Reports
سال: 2017
ISSN: 1757-790X
DOI: 10.1136/bcr-2016-217840